Ongoing Program to Improve Medication Use Management and Utilize PharmacoEconomics (OPTIMIZE). The best practice is a multidisciplinary collaborative approach of medication evaluation, pharmacoeconomic and clinical audit studies for new medications, generics and biosimilars added to the formulary, besides the existing medications to assure the most clinically-effective and cost-effective medication provided to our patients. OPTIMIZE consists of three basic frameworks to optimize medication use:

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